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Parkinson's disease

Mitochondrial damage control

Defects in mitochondria are implicated in Parkinson's disease. Study of a quality-control pathway involving the proteins PINK1 and Parkin provides further clues about the mechanism involved.

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Figure 1: Possible mechanism of mitochondrial monitoring by PINK1 and Parkin.

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Abeliovich, A. Mitochondrial damage control. Nature 463, 744–745 (2010). https://doi.org/10.1038/463744a

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