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From angiogenesis to lymphangiogenesis

Nature Medicine volume 7, pages 151–152 (2001)Cite this article

Vascular endothelial growth factors are well-known angiogenic agents and targets for anti-cancer therapies. Now it appears that this signaling pathway is also involved in developmental and tumor-induced lymphangiogenesis (pages 186-191, 192-198, 199-205).

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Figure 1: Dissecting tumor angiogenesis. Hypoxic tumor cells produce VEGF , which binds to and activates VEGFR-2 on vascular endothelial cells, leading to classical tumor angiogenesis.

Stephen Horwitz

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  1. Department of Neuropathology Institute of Pathology, FAU, Erlangen-Nürnberg, Germany

    Karl H. Plate

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  1. Karl H. Plate
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Plate, K. From angiogenesis to lymphangiogenesis. Nat Med 7, 151–152 (2001). https://doi.org/10.1038/84579

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