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Serum levels of folate, lycopene, β-carotene, retinol and vitamin E and prostate cancer risk

European Journal of Clinical Nutrition volume 64, pages 1235–1238 (2010)Cite this article

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Abstract

Previous studies relating increased serum levels of folate and fat-soluble vitamins to prostate cancer risk have variously shown null associations or to either decrease or increase the risk of developing prostate cancer. Prospective studies of serum folate levels have been reported to show a null association and increased serum levels to either decrease or increase the risk of subsequently developing prostate cancer. Similarly, serum β-carotene and lycopene levels have either been reported to be inversely correlated or not associated with prostate cancer risk. Using a prospective nested case-control study design, which minimized the possibility of disease effects on serum-vitamin concentrations, we report null associations for serum concentrations of folate, lycopene, β-carotene, vitamin A and vitamin E, and subsequent development of prostate cancer.

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Authors and Affiliations

  1. Biochemistry Section, PathWest, Queen Elizabeth II Medical Centre, Nedlands, WA, Australia

    J Beilby & E Rossi

  2. School of Population Health, University of Western Australia, Nedlands, WA, Australia

    G L Ambrosini & A W Musk

  3. Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Nedlands, WA, Australia

    N H de Klerk

  4. Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA, Australia

    A W Musk

Authors
  1. J Beilby
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  2. G L Ambrosini
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  3. E Rossi
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  4. N H de Klerk
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  5. A W Musk
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Correspondence to E Rossi.

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Beilby, J., Ambrosini, G., Rossi, E. et al. Serum levels of folate, lycopene, β-carotene, retinol and vitamin E and prostate cancer risk. Eur J Clin Nutr 64, 1235–1238 (2010). https://doi.org/10.1038/ejcn.2010.124

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  • DOI: https://doi.org/10.1038/ejcn.2010.124

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