Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Original Article
  • Published:

Despite evidence-based guidelines, systolic blood pressure remains inadequately controlled in older hypertensive adults

Abstract

We aimed to assess the trends in the prevalence, awareness, treatment and control of hypertension in Finnish men and women aged 60–74 years. Three independent cross-sectional population surveys were conducted in 1997, 2002 and 2007 in the province of North Karelia and the region of Helsinki–Vantaa. Random samples were selected from the national population register. The total number of participants was 3282. In 2007, the prevalence of hypertension was 79% in men and 78% in women. The mean systolic blood pressure (SBP) (in men, 151 mm Hg in 1997, 148 mm Hg in 2002 and 149 mm Hg in 2007; in women 150, 149 and 149 mm Hg, respectively) and prevalence of hypertension (77% in 1997, 74% in 2002 and 79% in 2007 in men; 75, 75 and 78% in women, respectively) remained stable. The mean diastolic blood pressure (BP) decreased in both genders. Awareness of hypertension increased from 60 to 71% in men (P<0.001 for trend) and from 66 to 76% (P=0.012) in women. The prevalence of antihypertensive drug treatment among hypertensive people increased from 35 to 56% in both genders (P<0.001). The proportion of treated hypertensive patients with adequately controlled BP increased from 16 to 32% in men (P<0.001) and from 16 to 30% in women (P=0.003). Hypertension care in older adults has improved in Finland during 1997 to 2007. The situation is not optimal: the main problem in this age group is high SBP.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G et al. 2007 Guidelines for the management of arterial hypertension. The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2007; 25: 1105–1187.

    Article  CAS  PubMed  Google Scholar 

  2. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL et al. And the national high blood pressure education program coordinating committee seventh report of the joint national committee on prevention, detection, evaluation and treatment of high blood pressure. Hypertension 2003; 42: 1206–1252.

    Article  CAS  PubMed  Google Scholar 

  3. Lawes CMM, Vander Hoorn S . Rodgers a for the international society of hypertension global burden of blood pressure-related diseases. Lancet 2008; 371: 1513–1518.

    Article  PubMed  Google Scholar 

  4. Wolf-Maier K, Cooper R, Banagas JR, Giampaoli S, Hense H-W, Joffres M et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada and the United States. JAMA 2003; 289: 2263–2369.

    Article  Google Scholar 

  5. Thijs L, Fagard R, Lijnen P, Staessen J, van Hoof R, Amery A . A meta-analysis of outcome trials in elderly hypertensives. J Hypertens 1992; 10: 1103–1109.

    Article  CAS  PubMed  Google Scholar 

  6. Kannel WB . Elevated systolic blood pressure as a cardiovascular risk factor. Am J Cardiol 2000; 85: 251–255.

    Article  CAS  PubMed  Google Scholar 

  7. Staessen JA, Gasowski J, Wang JG, Thijs L, den Hond ED, Boissel J-P et al. Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials. Lancet 2000; 355: 865–872.

    Article  CAS  PubMed  Google Scholar 

  8. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R . Prospective study collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903–1913.

    Article  PubMed  Google Scholar 

  9. Franklin SS, Larson MG, Khan SA, Wong ND, Leip EP, Kannel WB et al. Does the relation of blood pressure to coronary heart disease change with aging? The Framingham Heart Study. Circulation 2001; 103: 1245–1249.

    Article  CAS  PubMed  Google Scholar 

  10. Kannel WB, Gordon T, Schwartz MJ . Systolic versus diastolic blood pressure and risk of coronary heart disease. The Framingham Study. Am J Cardiol 1971; 27: 335–346.

    Article  CAS  PubMed  Google Scholar 

  11. The Joint National Committee on Prevention Detection Evaluation reatment of High Blood Pressure. The Fifth Report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 1993; 153: 154–183.

    Article  Google Scholar 

  12. Suomen sydäntautiliiton työryhmän kannanotto. Kohonneen verenpaineen ehkäisy. Suom Lääkl 1994; 49: 1831–1840.

    Google Scholar 

  13. Guidelines committee. 2003 European Society of Hypertension-of the European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011–1053.

    Article  Google Scholar 

  14. WHO Monica Project. MONICA manual, part III: population survey, Available at http://www.ktl.fi/publications/monica/manual/part3/iii-1htm. Accessed 2 February 2006.

  15. Tolonen H, Kuulasmaa K, Laatikainen T, Wolf H . Recommendation for indicators, international collaboration, protocol and manual operations of chronic disease risk factor surveys 2002; Available at http://www.ktl.fi/ehrm; Accessed: 2 February 2006.

  16. Friedewald WT, Levy RI, Fredrickson DS . Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499–502.

    CAS  PubMed  Google Scholar 

  17. Antikainen RL, Moltchanov VA, Chukwuma Sr C, Kuulasmaa KA, Marques-Vidal PM, Sans S et al. for the WHO MONICA Project; Trends in the prevalence, awareness, treatment and control of hypertension: the WHO MONICA Project. Eur J Cardiovasc Prev Rehabil 2006; 13: 13–29.

    PubMed  Google Scholar 

  18. Primatesta P, Poulter NR . Improvement in hypertension in England: results from the Health Survey for England. J Hypertens 2006; 24: 1187–1192.

    Article  CAS  PubMed  Google Scholar 

  19. Ostchega Y, Dillon CF, Hughes JP, Carroll M, Yoon S . Trends in hypertension prevalence, awareness, treatment, and control in older US. Adults: Data from the National Health and Nutrition Examination Survey 1988–2004. J Am Geriatr Soc 2007; 55: 1056–1065.

    Article  PubMed  Google Scholar 

  20. Su T-C, Bai C-H, Chang H-Y, You S-L, Chien K-Li, Cheng M-F et al Evidence for improved control of hypertension in Taiwan: 1993–2002. J Hypertens 2008; 26: 600–606.

    Article  CAS  PubMed  Google Scholar 

  21. Gu D, Reynolds K, Wu X, Chen J, Duan X, Muntner P et al. Interasia collaborative group. The international collaborative study of cardiovascular disease in Asia. prevalence, awareness, treatment, and control of hypertension in China. Hypertension 2002; 40: 920–927.

    Article  CAS  PubMed  Google Scholar 

  22. Banegas JR, Rodríguez-Artalejo F, Ruilope LM, Graciani A, Luque M, de la Cruz-Troca JJ et al. Hypertension magnitude and management in the elderly population of Spain. J Hypertens 2002; 20: 2157–2164.

    Article  CAS  PubMed  Google Scholar 

  23. Fasce E, Campos I, Ibáñez P, Flores M, Zárate H, Román O et al. Trends in prevalence, awareness, treatment and control of hypertension in urban communities in Chile. J Hypertens 2007; 25: 1807–1811.

    Article  CAS  PubMed  Google Scholar 

  24. Ong KL, Cheung BMY, Man YB, Lau CP, Lam KSL . Prevalence, awareness, treatment and control among United States Adults 1999–2004. Hypertension 2007; 49: 69–75.

    Article  CAS  PubMed  Google Scholar 

  25. Macedo ME, Lima MJ, Silva AO, Alcantara P, Ramalhinho V, Carmona J . Prevalence, awareness, treatment and control of hypertension in Portugal: the PAP study. J Hypertens 2005; 23: 1661–1666.

    Article  CAS  PubMed  Google Scholar 

  26. Falaschetti E, Chaudhury M, Mindell J, Poulter N . Continued improvement in Hypertension Management in England. Results from Health Survey for England 2006. Hypertension 2009; 53: 480–486.

    Article  CAS  PubMed  Google Scholar 

  27. Cutler JA, Sorlie PD, Wolz M, Thom T, Fields LE, Roccella EJ . Trends in hypertension prevalence, awareness, treatment and control rates in United States adults between 1988–1994 and 1999–2004. Hypertension 2008; 52: 818–827.

    Article  CAS  PubMed  Google Scholar 

  28. Wyatt SB, Akylbekova EL, Wofford MR, Coady SA, Walker ER, Andrew ME et al. Prevalence, awareness, treatment and control of hypertension in the Jackson Heart Study. Hypertension 2008; 51: 650–656.

    Article  CAS  PubMed  Google Scholar 

  29. Wang YR, Alexander GC, Stafford RS . Outpatient hypertension treatment, treatment intensification and control in Western Europe and the United States. Arch Intern Med 2007; 167: 141–147.

    Article  PubMed  Google Scholar 

  30. Kastarinen M, Antikainen R, Peltonen M, Laatikainen T, Barengo N, Jula A et al. Prevalence, awareness and treatment of hypertension in Finland during 1982–2007. J Hypertens 2009; 27: 1552–1559.

    Article  CAS  PubMed  Google Scholar 

  31. Kastarinen MJ, Antikainen RL, Laatikainen TK, Salomaa VV, Tuomilehto JO, Nissinen AM et al. Trends in hypertension care in eastern and south-western Finland during 1982–2002. J Hypertens 2006; 24: 829–836.

    Article  CAS  PubMed  Google Scholar 

  32. Cushman WC, Ford CE, Cutler JA, Margolis K, Davis BR, Grimm RM et al. for the ALLHAT Collaborative Research Group##Success and predictors of blood pressure control in diverse North American settings: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). J Clin Hypertens 2002; 4: 393–404.

    Article  Google Scholar 

  33. Wang TJ, Vasan R . Epidemiology of uncontrolled hypertension. Circulation 2005; 112: 1651–1662.

    Article  PubMed  Google Scholar 

  34. Mancia G, Grassi G . Systolic and diastolic blood pressure control in antihypertensive drug trials. J Hypertens 2002; 20: 1461–1464.

    Article  CAS  PubMed  Google Scholar 

  35. Fagard RH, Staessen JA, Thijs L, Celis H, Bulpitt CJ, de Leeuw P et al. On-treatment diastolic blood pressure and prognosis in systolic hypertension. Arch Intern Med 2007; 167: 1884–1891.

    Article  PubMed  Google Scholar 

  36. Boutitie F, Gueyffier F, Pocock S, Fagard P, Boissel JP . J-shaped relationship between blood pressure and mortality in hypertensive patients: new insight from a meta-analyses of individual-patient data. Ann Intern Med 2002; 136: 438–448.

    Article  PubMed  Google Scholar 

  37. Somes GW, Pahor M, Shorr RI, Cushman WC, Applegate WB . The role of diastolic blood pressure when treating isolated systolic hypertension. Ann Intern Med 1999; 159: 2004–2008.

    Article  CAS  Google Scholar 

  38. Tuomilehto J, Ryynänen O-P, Koistinen A, Rastenyte D, Nissinen A, Puska P . Low diastolic blood pressure and mortality in a population-based cohort of 16 913 hypertensive patients in North Karelia, Finland. J Hypertens 1998; 16: 1235–1242.

    Article  CAS  PubMed  Google Scholar 

  39. Wang J-G, Staessen JA, Franklin SS, Fagard R, Gueyffier F . Systolic and diastolic blood pressure lowering as determinants of cardiovascular outcome. Hypertension 2005; 45: 907–913.

    Article  CAS  PubMed  Google Scholar 

  40. Kannel WB, Vasan RS . Aggressive lowering of blood pressure. Lancet 2006; 368: 627–628.

    Article  PubMed  Google Scholar 

  41. Bailey KR, Grossardt BR, Graves JW . Novel use of Kaplan–Meier methods to explain age and gender differences in hypertension control rates. Hypertension 2008; 51: 841–847.

    Article  CAS  PubMed  Google Scholar 

  42. Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu AW . Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases. Implications for pay for performance. JAMA 2005; 294: 716–724.

    Article  CAS  PubMed  Google Scholar 

  43. Wang PS, Avorn J, Brookhart MA, Mogun H, Schneeweiss S, Fischer MA et al. Effects of noncardiovascular comorbidities on antihypertensive use in elderly hypertensives. Hypertension 2005; 46: 273–279.

    Article  PubMed  Google Scholar 

  44. Turner BJ, Hollenbeak CS, Weiner M, Ten Have T, Tang SSK . Effect on unrelated comorbid conditions on hypertension management. Ann Intern Med 2008; 148: 578–586.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This study was supported by grants from the Finnish Academy 119681, the Finnish Cardiovascular Research Foundation and the Social Welfare and Health Board, City of Oulu.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to R L Antikainen.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Antikainen, R., Kastarinen, M., Jousilahti, P. et al. Despite evidence-based guidelines, systolic blood pressure remains inadequately controlled in older hypertensive adults. J Hum Hypertens 24, 439–446 (2010). https://doi.org/10.1038/jhh.2009.85

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jhh.2009.85

Keywords

This article is cited by

Search

Quick links