Abstract
Infertility or reduced fertility in genetically modified mouse strains represents a serious bottleneck for planned research projects. The authors describe simple methods for troubleshooting poor reproductive performance in breeding colonies and introduce various means of assisted reproduction that might be used to 'rescue' infertile lines.
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Murray, K., Parker, N. Breeding genetically modified rodents: tips for tracking and troubleshooting reproductive performance. Lab Anim 34, 36–41 (2005). https://doi.org/10.1038/laban0405-36
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DOI: https://doi.org/10.1038/laban0405-36
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