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A global view of epistasis

Nature Genetics volume 37, pages 13–14 (2005)Cite this article

Epistasis is a phenomenon whereby the effects of a given gene on a biological trait are masked or enhanced by one or more other genes. A new study documents epistasis among 890 metabolic genes in yeast, providing one of the largest data sets of its kind in any model organism.

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Figure 1: Genetical, biological and statistical epistasis.

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Authors and Affiliations

  1. Departments of Genetics and Community and Family Medicine, HB7937, One Medical Center Dr., Dartmouth Medical School, Lebanon, 03756, New Hampshire, USA

    Jason H Moore

  2. Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire, USA

    Jason H Moore

  3. Department of Computer Science at the University of New Hampshire, Durham, New Hampshire, USA

    Jason H Moore

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  1. Jason H Moore
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Moore, J. A global view of epistasis. Nat Genet 37, 13–14 (2005). https://doi.org/10.1038/ng0105-13

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