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A new identity for the elusive intestinal stem cell

The tremendous regenerative power of the intestinal epithelium has attracted considerable attention to the crypt as a model for adult stem cell biology. A new study now identifies the Polycomb group protein Bmi1 as a specific marker of intestinal stem cells in vivo.

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Figure 1: Section of a mouse small intestine stained with hematoxylin and eosin.

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Batlle, E. A new identity for the elusive intestinal stem cell. Nat Genet 40, 818–819 (2008). https://doi.org/10.1038/ng0708-818

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