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From cilia to cyst

Nephronophthisis is the most common inherited cause of renal failure in children. Two new studies add to the growing body of literature that suggests that cilial dysfunction may underlie all forms of cystic renal disease.

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Figure 1: Subcellular localization of cystoproteins.

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Watnick, T., Germino, G. From cilia to cyst. Nat Genet 34, 355–356 (2003). https://doi.org/10.1038/ng0803-355

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