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EMPReSS: standardized phenotype screens for functional annotation of the mouse genome

Nature Genetics volume 37, page 1155 (2005)Cite this article

An Author Correction to this article was published on 15 February 2022

This article has been updated

To the editor:

With the completion of the genome sequence of several mammals, attention is now focused on functional annotation of these genomes. The most versatile organism in which to study mammalian gene function is the mouse, as there is an extensive tool kit for modifying the genome including gene-driven and phenotype-driven approaches1,2,3,4,5,6. Underpinning this diversity is the recognition of the utility of a series of mutated alleles at every gene in the mouse genome. Such a resource would enable a full exploration of gene-phenotype space and provide a wider collection of models for translating gene function to human disease genetics. Such a program is crucially dependent on tools to investigate phenotype.

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Change history

  • 22 August 2006

    In the supplementary information initially published online to accompany this article, the name of one of the contributors was inadvertently omitted from the Supplementary Note. The original file has been replaced with a corrected version. The error has been corrected online

  • 15 February 2022

    A Correction to this paper has been published: https://doi.org/10.1038/s41588-022-01019-w

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Author notes

  1. S.D.M. Brown, P. Chambon and M. Hrabé de Angelis: contributed equally to this work.

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The Eumorphia Consortium

  • S.D.M. Brown
  • , P. Chambon
  •  & M. Hrabé de Angelis

Additional information

A list of all members of The Eumorphia Consortium and their affiliations is given in Supplementary Note online.

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The Eumorphia Consortium. EMPReSS: standardized phenotype screens for functional annotation of the mouse genome. Nat Genet 37, 1155 (2005). https://doi.org/10.1038/ng1105-1155

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