Four genome-wide association studies report associations to a range of clinically relevant hematological traits. The candidate genes identified include many that are known to be important in iron homeostasis and red blood cell maturation.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
High-dimensional phenotyping to define the genetic basis of cellular morphology
Nature Communications Open Access 06 January 2024
-
Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies
Nature Communications Open Access 31 July 2020
-
Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease
Genome Medicine Open Access 28 June 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Meisinger, C. et al. Am. J. Hum. Genet. 84, 66–71 (2009).
Evans, D.M. et al. J. Allergy Clin. Immunol. 114, 826–830 (2004).
Soranzo, N. et al. Nat. Genet. 41, 1182–1190 (2009).
Ganesh, S.K. et al. Nat. Genet. 41, 1191–1198 (2009).
Chambers, J.C. et al. Nat. Genet. 41, 1170–1172 (2009).
Benyamin, B. et al. Nat. Genet. 41, 1173–1175 (2009).
Silvestri, L. et al. Cell Metab. 8, 502–511 (2008).
Babitt, J.L. et al. Nat. Genet. 38, 531–539 (2006).
Andrews, N.C. Blood 112, 219–230 (2008).
Du, X. et al. Science 320, 1088–1092 (2008).
Finberg, K.E. et al. Nat. Genet. 40, 569–571 (2008).
Barton, J.C., Bertoli, L.F. & Rothenberg, B.E. Genet. Test. 4, 103–110 (2000).
Levy, J.E., Jin, O., Fujiwara, Y., Kuo, F. & Andrews, N.C. Nat. Genet. 21, 396–399 (1999).
Lettre, G. et al. Proc. Natl. Acad. Sci. USA 105, 11869–11874 (2008).
Kaushansky, K. Blood 111, 981–986 (2008).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Andrews, N. Genes determining blood cell traits. Nat Genet 41, 1161–1162 (2009). https://doi.org/10.1038/ng1109-1161
Issue Date:
DOI: https://doi.org/10.1038/ng1109-1161
This article is cited by
-
High-dimensional phenotyping to define the genetic basis of cellular morphology
Nature Communications (2024)
-
Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies
Nature Communications (2020)
-
Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease
Genome Medicine (2018)
-
Anaemia in inflammatory rheumatic diseases
Nature Reviews Rheumatology (2013)
-
Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III)
BMC Medical Genetics (2012)