The runt-domain family of transcription factors (RUNX) have long been known to have a role in leukemogenesis and neoplasia. New evidence suggests a central role for these proteins in the development of autoimmunity.
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Alarcón-Riquelme, M. A RUNX trio with a taste for autoimmunity. Nat Genet 35, 299–300 (2003). https://doi.org/10.1038/ng1203-299
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DOI: https://doi.org/10.1038/ng1203-299
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