Macrophages infected with human immunodeficiency virus type 1 emit long intercellular conduits that shuttle the viral protein Nef to bystander B cells, where it impairs cellular function and immunoglobulin class switching.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Perspective on nanochannels as cellular mediators in different disease conditions
Cell Communication and Signaling Open Access 08 November 2018
-
Profile of blood cell abnormalities among antiretroviral therapy naïve HIV patients attending the Yaounde University Teaching Hospital, Cameroon
BMC Hematology Open Access 08 September 2014
-
Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation
Retrovirology Open Access 22 June 2012
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Moir, S. & Fauci, A.S. Nat. Rev. Immunol. 9, 235–245 (2009).
Xu, W. et al. Nat. Immunol. 10, 1008–1017 (2009).
Qiao, X. et al. Nat. Immunol. 7, 302–310 (2006).
He, B. et al. J. Immunol. 176, 3931–3941 (2006).
Thoulouze, M.I. et al. Immunity 24, 547–561 (2006).
Malim, M.H. & Emerman, M. Cell Host Microbe 3, 388–398 (2008).
Swingler, S. et al. Nature 424, 213–219 (2003).
Swingler, S. et al. Cell Host Microbe 4, 63–76 (2008).
Eugenin, E.A., Gaskill, P.J. & Berman, J.W. Cell. Immunol. 254, 142–148 (2009).
Sherer, N.M. & Mothes, W. Trends Cell Biol. 18, 414–420 (2008).
Sowinski, S. et al. Nat. Cell Biol. 10, 211–219 (2008).
Rudnicka, D. et al. J. Virol. 83, 6234–6246 (2009).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Rudnicka, D., Schwartz, O. Intrusive HIV-1-infected cells. Nat Immunol 10, 933–934 (2009). https://doi.org/10.1038/ni0909-933
Issue Date:
DOI: https://doi.org/10.1038/ni0909-933
This article is cited by
-
Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes
Journal of Cell Communication and Signaling (2019)
-
Perspective on nanochannels as cellular mediators in different disease conditions
Cell Communication and Signaling (2018)
-
Profile of blood cell abnormalities among antiretroviral therapy naïve HIV patients attending the Yaounde University Teaching Hospital, Cameroon
BMC Hematology (2014)
-
Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation
Retrovirology (2012)