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Angiotensin II and JAK2 put on the pressure

Researchers have long known that the peptide angiotensin II is central to blood pressure control—but there is yet more to learn. A new study shows how angiotensin II cooperates with the JAK2 kinase, better known for its role in cytokine signaling, to regulate blood vessel contraction and influence blood pressure (pages 183–190).

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Figure 1: The contraction of blood vessel smooth muscle by angiotensin II.

Katie Vicari

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Correspondence to Kenneth E Bernstein.

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Bernstein, K., Fuchs, S. Angiotensin II and JAK2 put on the pressure. Nat Med 16, 165–166 (2010). https://doi.org/10.1038/nm0210-165

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