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Sizing up miRNAs as cancer genes

Findings over the last year or so have built the case that microRNAs might contribute to cancer. Three studies now definitively show this to be the case and also suggest that these small RNAs could be used to categorize tumors.

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Figure 1: A model of miRNA involvement in cancer by modulation of expression of tumor suppressor genes and oncogenes.

Katie Ris

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Caldas, C., Brenton, J. Sizing up miRNAs as cancer genes. Nat Med 11, 712–714 (2005). https://doi.org/10.1038/nm0705-712

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