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Life on the inside for Mycobacterium tuberculosis

Nature Medicine volume 9, pages 1356–1357 (2003)Cite this article

M. tuberculosis persists in the body, sequestered inside macrophages and subverting the phagocytic machinery to create a membrane-bound home. Microarray profiling studies reveal how the bacterium settles into its new environment.

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Figure 1: M. tuberculosis moves in.
Figure 2: Estimated tuberculosis (TB) incidence rates, 2001, as reported by the World Health Organization.

Reprinted from WHO

References

  1. Armstrong, J.A. & Hart, P.D. J. Exp. Med. 134, 713–740 (1971).

    Article  CAS  Google Scholar 

  2. Schnappinger, D. et al. J. Exp. Med. 198, 693–704 (2003).

    Article  CAS  Google Scholar 

  3. Voskuil, M.I. J. Exp. Med. 198, 705–713 (2003).

    Article  CAS  Google Scholar 

  4. MacMicking, J.D. et al. Proc. Natl. Acad. Sci. USA 94, 5243–5248 (1997).

    Article  CAS  Google Scholar 

  5. MacMicking, J.D., Taylor, G.A. & McKinney, J.D. Science (in the press).

  6. Fisher, M.A., Plikaytis, B.B. & Shinnick, T.M. J. Bacteriol. 184, 4025–4032 (2002).

    Article  CAS  Google Scholar 

  7. Dye, C. et al. JAMA 282, 677–686 (1999).

    Article  CAS  Google Scholar 

  8. Flynn, J.L. & Chan, J. Infect. Immun. 69, 4195–4201 (2001).

    Article  CAS  Google Scholar 

  9. Shi, L. et al. Proc. Natl. Acad. Sci. USA 100, 241–246 (2003).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Laboratory of Infection Biology, The Rockefeller University, 1230 York Avenue, New York, 10021, New York, USA

    John D McKinney & James E Gomez

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  1. John D McKinney
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  2. James E Gomez
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McKinney, J., Gomez, J. Life on the inside for Mycobacterium tuberculosis. Nat Med 9, 1356–1357 (2003). https://doi.org/10.1038/nm1103-1356

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