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Single-molecule mountains yield nanoscale cell images

Methods to simultaneously localize the positions of multiple single fluorophores by precisely determining their individual positions are now yielding impressive gains in fluorescence microscopy resolution.

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Figure 1: Measuring mountain peaks for superresolution imaging.

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Moerner, W. Single-molecule mountains yield nanoscale cell images. Nat Methods 3, 781–782 (2006). https://doi.org/10.1038/nmeth1006-781

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