Abstract
The laboratory mouse has long been an important tool in the study of the biology and genetics of human cancer. With the advent of genetic engineering techniques, DNA microarray analyses, tissue arrays and other large-scale, high-throughput data generating methods, the amount of data available for mouse models of cancer is growing exponentially. Tools to integrate, locate and visualize these data are crucial to aid researchers in their investigations. The Mouse Tumor Biology database (http://tumor.informatics.jax.org) seeks to address that need.
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Acknowledgements
For critical reading of the manuscript we thank K. Mills and B. Tennent of the The Jackson Laboratory, Bar Harbor, USA. For sample images in FIG. 4 we thank J. Ward of the National Cancer Institute. The Mouse Tumor Biology Database is supported by grant CA089713 from the National Cancer Institute. Images generated from The Jackson Aging Center projects are supported by a grant from the Ellison Medical Foundation.
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Krupke, D., Begley, D., Sundberg, J. et al. The Mouse Tumor Biology database. Nat Rev Cancer 8, 459–465 (2008). https://doi.org/10.1038/nrc2390
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DOI: https://doi.org/10.1038/nrc2390
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