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Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells

Bone Marrow Transplantation volume 26, pages 797–800 (2000)Cite this article

Abstract

We report a case of posterior reversible leuko- encephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing’s sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months. Bone Marrow Transplantation (2000) 26, 797–800.

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Acknowledgements

We thank Dr Georgia Vogelsang for her comments on the paper.

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Authors and Affiliations

  1. Departments of Oncology and Pediatrics, Johns Hopkins Hospital, Baltimore, MD, USA

    MA Higman & AR Chen

  2. Russell H Morgan Department of Radiology, Johns Hopkins Hospital, Baltimore, MD, USA

    JD Port & NJ Beauchamp Jr

Authors
  1. MA Higman
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  2. JD Port
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  3. NJ Beauchamp Jr
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  4. AR Chen
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Higman, M., Port, J., Beauchamp, N. et al. Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells. Bone Marrow Transplant 26, 797–800 (2000). https://doi.org/10.1038/sj.bmt.1702589

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  • DOI: https://doi.org/10.1038/sj.bmt.1702589

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