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Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid

European Journal of Clinical Nutrition volume 55, pages 499–508 (2001)Cite this article

Abstract

Objective: To investigate the effect of 2 week use of oils high in linoleic (LA), γ-linolenic (GLA) and oleic acid (OA) on energy intake (EI), macronutrient composition, parameters of appetite and taste perception.

Design: A randomized placebo-controlled 2-week treatment, followed by a test day.

Setting: Two-week treatments, daily life; test day, laboratory restaurant.

Subjects: Eight overweight men and eight overweight women (body mass index 27.4±1.5 kg/m2).

Interventions: Three 2 week treatments, in which subjects replaced their habitual fat products by three different oils (relatively) high in LA (66.8%), GLA (20.2%) or OA (79.6%, placebo). The wash-out periods were 2 weeks. Before each intervention period, taste perception and sensory specific satiety was tested.

Results: Even though energy intake was higher during dinner, subjects ate relatively less fat with LA (45.0±9.4 E%, P<0.05) than with OA (48.3±8.3 E%). Subjects did not distinguish the oils with the different fatty acids from each other. There was no relation between satiety or fat-specific satiety and taste characterization without as well as with sucrose. Although no differences were seen for the AUC of the appetite profile, aet 15:00 h subjects were less satiated with LA (46.1±6.2 mm, P<0.05) or GLA (45.1±5.8 mm, P<0.01) than after treatment OA (62.5±4.8 mm). 24 h EI on the test day was 7.6–8.0 MJ and did not differ between treatments.

Conclusions: Fat-specific satiety during dinner with LA vs OA was shown after a 2-week treatment of each oil, but no change in general satiety. Fat specific satiety was not related to taste perception or characterization of the oils.

Sponsorship: Novartis Consumer Health, Ltd, Nyon, Switzerland.

European Journal of Clinical Nutrition (2001) 55, 499–508

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  1. MS Westerterp-Plantenga: Guarantor: MS Westerterp-Plantenga.

  2. MMJW Kamphuis and MS Westerterp-Plantenga: Contributors: MMJW Kamphuis executed the study, supervised by MS Westerterp-Plantenga, and wrote the manuscript, which was revised by MS Westerterp-Plantenga and WHM Saris.

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  1. Department of Human Biology, Maastricht University, Maastricht, The Netherlands

    MMJW Kamphuis, MS Westerterp-Plantenga & WHM Saris

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Kamphuis, M., Westerterp-Plantenga, M. & Saris, W. Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. Eur J Clin Nutr 55, 499–508 (2001). https://doi.org/10.1038/sj.ejcn.1601222

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