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The role of E2A-PBX1 in leukemogenesis

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References

  • Abu-Shaar M, Ryoo HD, Mann RS . 1999 Genes Dev. 13: 935–945

  • Aronheim A, Shiran R, Rosen A, Walker MD . 1993 Proc. Natl. Acad. Sci. USA 90: 8063–8067

  • Aspland SE, White RAH . 1997 Development 124: 741–747

  • Austin TW, Solar GP, Ziegler FC, Liem L, Matthews W . 1997 Blood 89: 3624–3635

  • Bain G, Engel I, Robanus Maandag EC, te Riele HP, Voland JR, Sharp LL, Chun J, Huey B, Pinkel D, Murre C . 1997 Mol. Cell. Biol. 17: 4782–4791

  • Bain G, Gruenwald S, Murre C . 1993 Mol. Cell. Biol. 13: 3522–3529

  • Bain G, Maandag EC, Izon DJ, Amsen D, Kruisbeek AM, Weintraub BC, Krop I, Schlissel MS, Feeney AJ, van Roon M, et al. 1994 Cell 79: 885–892

  • Bain G, Romanow WJ, Albers K, Havran WL, Murre C . 1999 J. Exp. Med. 189: 289–300

  • Barndt RJ, Dai M, Zhuang Y . 2000 Mol. Cell. Biol. 20: 6677–6685

  • Bayly R, LeBrun DP . 2000 Mol. Cell. Biol. 20: 5789–5796

  • Berthelsen J, Kilstrup-Nielsen C, Blasi F, Mavilio F, Zappavigna V . 1999 Genes Dev. 13: 946–953

  • Borrow J, Shearman AM, Stanton VP, Becher R, Collins T, Williams AJ, Dube I, Katz F, Kwong YL, Morris C, Ohyashiki K, Toyama K, Rowley J, Housman DE . 1996 Nature Genetics 12: 159–167

  • Buske C, Humphries RK . 2000 Int. J. Hematol. 71: 301–308

  • Calvo KR, Knoepfler P, McGrath S, Kamps MP . 1999 Oncogene 18: 8033–8043

  • Carroll AJ, Crist WM, Parmley RT, Roper M, Cooper MD, Finley WH . 1984 Blood 63: 721–724

  • Chang CP, Brocchieri L, Shen WF, Largman C, Cleary ML . 1996 Mol. Cell. Biol. 16: 1734–1745

  • Chang CP, De Vivo I, Cleary ML . 1997a Mol. Cell. Biol. 17: 81–88

  • Chang CP, Jacobs Y, Nakamura T, Jenkins NA, Copeland NG, Cleary ML . 1997b Mol. Cell. Biol. 17: 5679–5687

  • Chang CP, Shen WF, Rozenfeld S, Lawrence HJ, Largman C, Cleary ML . 1995 Genes Dev. 9: 663–674

  • Choi JK, Shen CP, Radomska HS, Eckhardt LA, Kadesch T . 1996 EMBO J. 15: 5014–5021

  • Chu C, Kohtz DS . 2000 J. Biol. Chem. 12: 12

  • Crist WM, Carroll AJ, Shuster JJ, Behm FG, Whitehead M, Vietti TJ, Look AT, Mahoney D, Ragab A, Pullen DJ. et al . 1990 Blood 76: 117–122

  • de Lau WBM, Hurenkamp J, Berendes P, Touw IP, Clevers HC, van Dijk MA . 1998 Oncogene 17: 503–510

  • Dedera DA, Waller EK, LeBrun DP, Sen-Majumdar A, Stevens ME, Barsh GS, Cleary ML . 1993 Cell 74: 833–843

  • Engel I, Murre C . 1999 Proc. Natl. Acad. Sci. USA 96: 996–1001

  • Feldman BJ, Hampton T, Cleary ML . 2000 Blood 96: 1906–1913

  • Feldman BJ, Reid TR, Cleary ML . 1997 Oncogene 15: 2735–2742

  • Flegel WA, Singson AW, Margolis JS, Bang AG, Posakony JW, Murre C . 1993 Mech. Dev. 41: 155–161

  • Fu X, Kamps MP . 1997 Mol. Cell. Biol. 17: 1503–1512

  • Fu X, McGrath S, Pasillas M, Nakazawa S, Kamps MP . 1999a Oncogene 18: 4920–4929

  • Fu X, Roberts WG, Nobile V, Shapiro R, Kamps MP . 1999b Growth Factors 17: 125–137

  • Goldfarb AN, Flores JP, Lewandowska K . 1996 Mol. Immunol. 33: 947–956

  • González-Crespo S, Abu-Shaar M, Torres M, Martinez-A C, Mann RS, Morata G . 1998 Nature 394: 196–200

  • Hunger SP, Galili N, Carroll AJ, Crist WM, Link MP, Cleary ML . 1991 Blood 15: 687–693

  • Jürgens G, Wieschaus E, Nüsslein-Volhard C, Kluding H . 1984 Roux's Arch. Dev. Biol. 193: 283–295

  • Kamps MP, Baltimore D . 1993 Mol. Cell. Biol. 13: 351–357

  • Kamps MP, Look AT, Baltimore D . 1991 Genes Dev. 5: 358–368

  • Kamps MP, Murre C, Sun XH, Baltimore D . 1990 Cell 60: 547–555

  • Kamps MP, Wright DD, Lu Q . 1996 Oncogene 12: 19–30

  • Kee BL, Murre C . 1998 J. Exp. Med. 188: 699–713

  • Kee BL, Quong MW, Murre C . 2000 Immunol. Rev. 175: 138–149

  • Knoepfler PS, Calvo KR, Chen H, Antonarakis SE, Kamps MP . 1997 Proc. Natl. Acad. Sci. USA 94: 14553–14558

  • Knoepfler PS, Kamps MP . 1995 Mol. Cell. Biol. 15: 5811–5819

  • Knoepfler PS, Kamps MP . 1997 Oncogene 14: 2521–2531

  • Kurant E, Pai CY, Sharf R, Halachmi N, Sun YH, Salzberg A . 1998 Development 125: 1037–1048

  • Lassar AB, Davis RL, Wright WE, Kadesch T, Murre C, Voronova A, Baltimore D, Weintraub H . 1991 Cell 66: 305–315

  • LeBrun DP, Cleary ML . 1994 Oncogene 9: 1641–1647

  • LeBrun DP, Matthews BP, Feldman BJ, Cleary ML . 1997 Oncogene 15: 2059–2067

  • Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H . 1995 Science 268: 836–844

  • Lu Q, Kamps MP . 1996 Proc. Natl. Acad. Sci. USA 93: 470–474

  • Lu Q, Kamps MP . 1997 Oncogene 14: 75–83

  • Lu Q, Knoepfler PS, Scheele J, Wright DD, Kamps MP . 1995 Mol. Cell. Biol. 15: 3786–3795

  • Lu Q, Wright DD, Kamps MP . 1994 Mol. Cell. Biol. 14: 3938–3948

  • Mann RS, Abu-Shaar M . 1996 Nature 383: 630–633

  • Massari ME, Grant PA, Pray-Grant MG, Berger SL, Workman JL, Murre C . 1999 Mol. Cell 4: 63–73

  • Massari ME, Jennings PA, Murre C . 1996 Mol. Cell. Biol. 16: 121–129

  • McWhirter JR, Goulding M, Weiner JA, Chun J, Murre C . 1997 Development 124: 3221–3232

  • McWhirter JR, Neuteboom STC, Wancewicz EV, Monia BP, Downing JR, Murre C . 1999 Proc. Natl. Acad. Sci. USA 96: 11464–11469

  • Monica K, Galili N, Nourse J, Saltman D, Cleary ML . 1991 Mol. Cell. Biol. 11: 6149–6157

  • Monica K, LeBrun DP, Dedera DA, Brown R, Cleary ML . 1994 Mol. Cell. Biol. 14: 8304–8314

  • Murre C, McCaw PS, Baltimore D . 1989a Cell 56: 777–783

  • Murre C, McCaw PS, Vaessin H, Caudy M, Jan LY, Jan YN, Cabrera CV, Buskin JN, Hauschka SD, Lassar AB. et al . 1989b Cell 58: 537–544

  • Nakamura T, Largaespada DA, Lee MP, Johnson LA, Ohyashiki K, Toyama K, Chen SJ, Willman CL, Chen I, Feinberg AP, Jenkins NA, Copeland NG, Shaughnessy JD . 1996 Nature Genetics 12: 154–158

  • Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ . 1997 Genes Dev. 11: 2323–2334

  • Neuteboom STC, Peltenburg LTC, Van Dijk MA, Murre C . 1995 Proc. Natl. Acad. Sci. USA 92: 9166–9170

  • Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD, Cleary ML . 1990 Cell 60: 535–545

  • Pai CY, Kuo TS, Jaw TJ, Kurant E, Chen CT, Bessarab DA, Salzberg A, Sun YH . 1998 Genes Dev. 12: 435–446

  • Park ST, Nolan GP, Sun XH . 1999 J. Exp. Med. 189: 501–508

  • Peifer M, Wieschaus E . 1990 Genes Dev. 4: 1209–1223

  • Peltenburg LT, Murre C . 1997 Development 124: 1089–1098

  • Peltenburg LTC, Murre C . 1996 EMBO J. 15: 3385–3393

  • Peverali FA, Ramqvist T, Saffrich R, Pepperkok R, Barone MV, Philipson L . 1994 EMBO J. 13: 4291–4301

  • Phelan ML, Rambaldi I, Featherstone MS . 1995 Mol. Cell. Biol. 15: 3989–3997

  • Polakis P . 2000 Genes Dev. 14: 1837–1851

  • Prabhu S, Ignatova A, Park ST, Sun XH . 1997 Mol. Cell. Biol. 17: 5888–5896

  • Qiu Y, Sharma A, Stein R . 1998 Mol. Cell. Biol. 18: 2957–2964

  • Quong MW, Harris DP, Swain SL, Murre C . 1999 EMBO J. 18: 6307–6318

  • Quong MW, Massari ME, Zwart R, Murre C . 1993 Mol. Cell. Biol. 13: 792–800

  • Rauskolb C, Peifer M, Wieschaus E . 1993 Cell 74: 1101–1112

  • Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, Grosschedl R . 2000 Immunity 13: 15–24

  • Rieckhof GE, Casares F, Ryoo HD, Abu-Shaar M, Mann RS . 1997 Cell 91: 171–183

  • Rivera RR, Johns CP, Quan J, Johnson RS, Murre C . 2000 Immunity 12: 17–26

  • Romanow WJ, Langerak AW, Goebel P, Wolvers-Tettero IL, van Dongen JJ, Feeney AJ, Murre C . 2000 Mol. Cell 5: 343–353

  • Schlissel M, Voronova A, Baltimore D . 1991 Genes Dev. 5: 1367–1376

  • Sen R, Baltimore D . 1986 Cell 46: 705–716

  • Shen CP, Kadesch T . 1995 Mol. Cell. Biol. 15: 4518–4524

  • Shimamoto T, Ohyashika K, Toyama K, Takeshita K . 1998 Int. J. Hematol. 67: 339–350

  • Sigvardsson M, O'Riordan M, Grosschedl R . 1997 Immunity 7: 25–36

  • Smith KS, Jacobs Y, Chang CP, Cleary ML . 1997 Oncogene 14: 2917–2926

  • Thorsteinsdottir U, Krosl J, Kroon E, Haman A, Hoang T, Sauvageau G . 1999 Mol. Cell. Biol. 19: 6355–6366

  • Thorsteinsdottir U, Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ, Largman C, Humphries RK . 1997 Mol. Cell. Biol. 17: 495–505

  • Van Den Berg DJ, Sharma AK, Bruno E, Hoffman R . 1998 Blood 92: 3189–3202

  • van Dijk MA, Murre C . 1994 Cell 78: 617–624

  • van Dijk MA, Peltenburg LTC, Murre C . 1995 Mech. Dev. 52: 99–108

  • van Dijk MA, Voorhoeve PM, Murre C . 1993 Proc. Natl. Acad. Sci. USA 90: 6061–6065

  • van Dongen JJ, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G, Gottardi E, Rambaldi A, Dotti G, Griesinger F, Parreira A, Gameiro P, Diaz MG, Malec M, Langerak AW, San Miguel JF, Biondi A . 1999 Leukemia 13: 1901–1923

  • Williams DL, Look AT, Melvin SL, Roberson PK, Dahl G, Flake T, Stass S . 1984 Cell 36: 101–109

  • Yan W, Young AZ, Soares VC, Kelley R, Benezra R, Zhuang Y . 1997 Mol. Cell. Biol. 17: 7317–7327

  • Zhuang Y, Soriano P, Weintraub H . 1994 Cell 79: 875–884

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Acknowledgements

We thank Henri Kester, Eben Massari, Melanie Quong and Camil Sayegh for helpful comments on this manuscript. This work is supported by grants from the National Institutes of Health (NIH). HH Bendall is an American Cancer Society Kirby Foundation Fellow.

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Aspland, S., Bendall, H. & Murre, C. The role of E2A-PBX1 in leukemogenesis. Oncogene 20, 5708–5717 (2001). https://doi.org/10.1038/sj.onc.1204592

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