Issue 3, 1997
From the journal:

Journal of the Chemical Society, Faraday Transactions

Intermolecular forces expressed in 1,2-dichloroethane–water partition coefficients

Guillaume Steyaert,   Guiseppe Lisa,   Patrick Gaillard,   Gilles Boss,   Frédéric Reymond,   Girault Hubert H,   Pierre-Alain Carrupt  and  Bernard Testa  

Abstract

The molecular parameters and intermolecular forces controlling partition coefficients (P) in the 1,2-dichloroethane (DCE)–water system have been studied. A set of 44 solutes was selected to allow a regular and broad exploration of property spaces. Log P dce values were measured by the shake-flask method, centrifugal partition chromatography, and/or the pH-metric method. Linear solvation Gibbs-energy relationship (LSER) analyses showed that log P dce values are controlled by the molecular volume of the solutes and by their H-bonding donor acidity and acceptor basicity, with a contribution from the latter parameters significantly greater than in n-octanol–water partition coefficients. The DCE–water system appears as a promising alternative to the alkane–water system for obtaining partition coefficients of interest in structure–permeation relationship studies.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/A606374H
Article type
Paper

J. Chem. Soc., Faraday Trans., 1997,93, 401-406

Permissions

Request permissions

Intermolecular forces expressed in 1,2-dichloroethane–water partition coefficients

G. Steyaert, G. Lisa, P. Gaillard, G. Boss, F. Reymond, G. Hubert H, P. Carrupt and B. Testa, J. Chem. Soc., Faraday Trans., 1997, 93, 401 DOI: 10.1039/A606374H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements