Issue 7, 2008
From the journal:

Molecular BioSystems

The incredible shrinking world of DNA microarrays

Sarah J. Wheelan,a   Francisco Martínez Murillo†bc  and  Jef D. Boekeabc  

a Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, USA

b Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, USA

c Microarray Core Facility, High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, USA

Abstract

The efficacy of microarrays in examining gene expression, gene and genome structure, protein–DNA interactions, whole-genome similarities and differences, microRNA expression, methylation (and more) is no longer in question. It is a fast-developing, cutting edge technology that has grown up along with massive sequence databases and is likely to become part of everyday patient care. Many advances have recently expanded the power and utility of microarrays; among them is our development of a new array tiling technique that dramatically increases the scope of coverage of an oligonucleotide tiling array without substantially increasing its cost.

Graphical abstract: The incredible shrinking world of DNA microarrays

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Article information

DOI
https://doi.org/10.1039/B706237K
Article type
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First published
17 Apr 2008

Mol. BioSyst., 2008,4, 726-732

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The incredible shrinking world of DNA microarrays

S. J. Wheelan, F. Martínez Murillo and J. D. Boeke, Mol. BioSyst., 2008, 4, 726 DOI: 10.1039/B706237K

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