Issue 1, 2011
From the journal:

Chemical Society Reviews

Biomedical applications of dendrimers: a tutorial

Meredith A. Mintzera  and  Mark W. Grinstaff*a  

* Corresponding authors

a Boston University, Departments of Biomedical Engineering and Chemistry, Metcalf Center for Science and Engineering, 590 Commonwealth Ave, Boston, USA
E-mail: mgrin@bu.edu
Fax: +1 617 358-3186
Tel: +1 617 358-3429

Abstract

Since their development in the mid-80s, dendrimers have become prominent synthetic macromolecules in the field of biomedical science. This tutorial review begins by discussing pertinent background information about dendrimers, focusing on their behavior in solution, how they are synthesized and what advantages they have over linear polymers. Then the focus of the review shifts to the biomedical applications of dendrimers, including their use in drug delivery, tissue engineering, gene transfection, and contrast enhancement for magnetic resonance imaging. This tutorial review is written for first-year graduate students or senior undergraduates and “asks” and “answers” many of the questions that arise in our first discussions of dendrimers.

Graphical abstract: Biomedical applications of dendrimers: a tutorial

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Article information

DOI
https://doi.org/10.1039/B901839P
Article type
Tutorial Review
Submitted
05 May 2010
First published
28 Sep 2010

Chem. Soc. Rev., 2011,40, 173-190

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Biomedical applications of dendrimers: a tutorial

M. A. Mintzer and M. W. Grinstaff, Chem. Soc. Rev., 2011, 40, 173 DOI: 10.1039/B901839P

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