Issue 7, 2010
From the journal:

Lab on a Chip

Wide field-of-view lens-free fluorescent imaging on a chip

Ahmet F. Coskun,a   Ting-Wei Sua  and  Aydogan Ozcan*ab  

* Corresponding authors

a Electrical Engineering Department, University of California, Los Angeles, CA, USA
E-mail: ozcan@ucla.edu
Web: http://www.innovate.ee.ucla.edu
Tel: +1 (310) 825-0915

b California NanoSystems Institute (CNSI), University of California, Los Angeles, CA, USA

Abstract

We demonstrate an on-chip fluorescent detection platform that can simultaneously image fluorescent micro-objects or labeled cells over an ultra-large field-of-view of 2.5 cm × 3.5 cm without the use of any lenses, thin-film filters and mechanical scanners. Such a wide field-of-view lensless fluorescent imaging modality, despite its limited resolution, might be very important for high-throughput screening applications as well as for detection and counting of rare cells within large-area microfluidic devices.

Graphical abstract: Wide field-of-view lens-free fluorescent imaging on a chip

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Article information

DOI
https://doi.org/10.1039/B926561A
Article type
Communication
Submitted
22 Dec 2009
Accepted
10 Feb 2010
First published
25 Feb 2010

Lab Chip, 2010,10, 824-827

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Wide field-of-view lens-free fluorescent imaging on a chip

A. F. Coskun, T. Su and A. Ozcan, Lab Chip, 2010, 10, 824 DOI: 10.1039/B926561A

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