* Corresponding authors

^a Laboratory of Hemostasis, Division of Hematology, Center for Biologic, Food and Drug Administration, Bethesda, Maryland 20892, USA
E-mail: Chava.kimchi-sarfaty@fda.hhs.gov

^b Laboratory of Plasma Derivatives, Division of Hematology, Center for Biologic, Food and Drug Administration, Bethesda, Maryland 20892, USA

^c First Research Department, The Chemo-Sero-Therapeutic Research Institute, Kumamoto, Japan

^d Division of Liver Diseases, Mount Sinai School of Medicine, New York, USA

^e Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
E-mail: Susan.Garfield@nih.hhs.gov

^f National Center for Biotechnology Information, National Library of Medicine, National Institute of Health, Bethesda, Maryland, USA
E-mail: Balaji_Santhanam@DFCI.HARVARD.EDU

^g Current Address: Department of Genetics, Harvard Medical School and Dept of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA