Issue 6, 1993

Modification of the binding affinity of peptide nucleic acids (PNA). PNA with extended backbones consisting of 2-aminoethyl-β-alanine or 3-aminopropylglycine units

Abstract

The binding affinity between peptide nucleic acids (PNA) and DNA is reduced by incorporation of PNA units with extended backbones.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1993, 518-519

Modification of the binding affinity of peptide nucleic acids (PNA). PNA with extended backbones consisting of 2-aminoethyl-β-alanine or 3-aminopropylglycine units

B. Hyrup, M. Egholm, M. Rolland, P. E. Nielsen, R. H. Berg and O. Buchardt, J. Chem. Soc., Chem. Commun., 1993, 518 DOI: 10.1039/C39930000518

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