Original researchFresh-frozen Osteochondral Allograft Reconstruction of a Giant Cell Tumor of the Talus
Section snippets
Case Report
A 34-year-old woman presented to a fellowship-trained orthopaedic oncologist (M. C. L.) after 2 failed procedures for giant cell tumor of the right talus. The tumor had been diagnosed a year earlier and failed 2 prior attempts at curettage and bone grafting. At the time of presentation to the orthopaedic oncologist, the patient had complaints of significant pain and limitation of ankle, as well as subtalar, motion. Because of the aggressive nature of the lesion, it was suggested that a more
Discussion
Giant cell tumor of the talus is a rare entity that has only been reported a handful of times in the orthopaedic literature (1, 2, 3, 4, 6, 12, 13). Nonetheless, it presents a difficult problem because the lesion is locally destructive, recurs even in the face of aggressive surgery, and, on occasion, may even metastasize. Murari et al found giant cell tumors to be the most common benign primary osseous neoplasms in the foot, comprising 19% of all lesions (12). The tumor is frequently found in
References (13)
- et al.
The diagnosis and management of osteochondral lesions of the talus: osteochondral allograft update
Arthroscopy
(2003) Stage VI: massive osteochondral defects of the talus
Foot Ankle Clin
(2004)- et al.
Giant cell tumor of the talus with secondary aneurysmal bone cyst
J Foot Ankle Surg
(1993) - et al.
Giant cell tumor of the talusA case report
Bull Hosp Jt Dis Orthop Inst
(1982) - et al.
Chemotherapy of a malignant, metastasizing giant-cell tumor of bone
Cancer
(1982) - et al.
Giant cell tumor and aneurysmal bone cyst of the talus: clinicopathological review and two case reports
Foot Ankle
(1981)
Cited by (17)
Reconstruction with β-tricalcium phosphate for giant cell tumor of the talus
2020, FootCitation Excerpt :In order to overcome the insufficient mechanical strength, cortical bone graft or fibular graft can be used [6]. Fresh-frozen osteochondral allograft reconstruction has also been used for GCTB of the talus [14], however the availability of the treatment is limited. β-TCP is a highly porous ceramic and has been developed as a bone substitute [15].
Giant Cell Tumor of the Talus: 19-Year Follow-Up of a Patient
2015, Journal of Foot and Ankle SurgeryCitation Excerpt :However, curettage alone has had a high rate of recurrence, and the use of adjuvant agents such as methyl methacrylate (bone cement), cryotherapy, and phenol have been reported. Several procedures, including fresh frozen osteochondral allografts (11), partial (3) or total excision (3,10) of the talus, and arthrodesis (3), have also been reported. The classic treatment of choice has been intralesional curettage.
Extended curettage and adjuvant therapy for benign tumors of the talus
2015, FootCitation Excerpt :Arthrodesis is essential after resection of all the tarsal bones except the calcaneum [9]. Fresh-frozen osteochondral allograft reconstruction has also been described for aggressive GCT of the talus, but the availability of the literature on this modality of treatment is limited [10]. We reviewed six cases of benign tumors of the talus for which talectomy and arthrodesis had been avoided.
Primary bone tumours of the talus: The Scottish Bone Tumour Registry experience
2012, Foot and Ankle SurgeryMatrix-associated Autologous Chondrocyte Transplantation Combined with Iliac Crest Bone Graft for Reconstruction of Talus Necrosis due to Villonodular Synovitis
2012, Journal of Foot and Ankle SurgeryCitation Excerpt :When reviewing the recent literature, we found several case reports about talar cartilage lesions, for example, those caused by osteochondrosis dissecans, and reports that discussed therapy with autologous chondrocyte transplantation (3,4). There were also several cases that reported on the treatment of talar osteonecrosis with bone allografts (5). We report a case of villonodular synovitis with an osteochondral defect characterized by persistent pain after an ankle distortion.
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Clinical Instructor, Department of Orthopaedic Surgery, Northeastern Ohio Universities College of Medicine, Resident, Department of Orthopaedic Surgery, Akron General Medical Center, Akron, OH
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Associate Professor, Department of Orthopaedic Surgery, Northeastern Ohio Universities College of Medicine, Residency Director, Department of Foot and Ankle Surgery, Saint Vincent’s Charity Hospital, Cleveland, OH, Attending Faculty, Department of Orthopaedic Surgery, Akron General Medical Center, Akron, OH
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Professor and Chair, Department of Orthopaedic Surgery, Northeastern Ohio Universities College of Medicine, Attending Faculty and Chairman, Department of Orthopaedic Surgery, Akron General Medical Center, Akron, OH