Journal of Biological Chemistry
Volume 272, Issue 23, 6 June 1997, Pages 14899-14907
NUCLEIC ACIDS, PROTEIN SYNTHESIS, AND MOLECULAR GENETICSSynergy between Interferon-γ and Tumor Necrosis Factor-α in Transcriptional Activation Is Mediated by Cooperation between Signal Transducer and Activator of Transcription 1 and Nuclear Factor κB*
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- *
This work was supported by U. S. Public Health Service Grant CA62220. The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
- 1
The abbreviations used are:
- IFN
interferon
- TNF
tumor necrosis factor
- STAT
signal transducer and activator of transcription
- SBE
STAT binding element
- IRF-1
interferon regulatory factor-1
- ICAM-1
intercellular adhesion molecule-1
- PCR
polymerase chain reaction
- IP-10
IFN-inducible protein
- 10 kDa
kb, kilobase pair
- NF-κB
nuclear factor κB
- TK
thymidine kinase
- CAT
chloramphenicol acetyltransferase
- EMSA
electrophoretic mobility shift assay
© 1997 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.