Journal of Biological Chemistry
Volume 272, Issue 47, 21 November 1997, Pages 29911-29918
CELL BIOLOGY AND METABOLISMA Molecular Basis for Insulin Resistance: ELEVATED SERINE/THREONINE PHOSPHORYLATION OF IRS-1 AND IRS-2 INHIBITS THEIR BINDING TO THE JUXTAMEMBRANE REGION OF THE INSULIN RECEPTOR AND IMPAIRS THEIR ABILITY TO UNDERGO INSULIN-INDUCED TYROSINE PHOSPHORYLATION*
Under a Creative Commons license
open access
Cited by (0)
- *
This work was supported by research grants from the Kekst Foundation (to Y. Z.), the Israel Ministry of Health (to Y. Z.), the Tolz Foundation (to Y. Z.), the Israel Cancer Research Fund (to H. K.), the Israel Cancer Association (to A. K.) and the Israel Science Foundation (founded by the Israel Academy of Sciences and Humanities) (to H. K., and A. K.) and by Grant 196130 from the Juvenile Diabetes Foundation International (to Y. Z.).The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
© 1997 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.