Journal of Biological Chemistry
Protein Structure and FoldingXRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair*♦
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The atomic coordinates and structure factors (code 3SR2) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
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This work was supported, in whole or in part, by National Institutes of Health Grant P01 CA92584 (Structural Cell Biology of DNA Repair Machines) (to J. A. T. and S. P. L.-M.). This work was also supported by Grant 69139 from the Canadian Institutes of Health Research and Grant 23817 from Alberta Cancer Foundation (to S. P. L.-M. and M. W.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental “Experimental Procedures,” “Results,” Figs. S1–S8, Tables S1, and additional references.
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