Journal of Biological Chemistry
Glycobiology and Extracellular MatricesCharacterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library*
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Addendum—During the review process of this manuscript, we reviewed the recent paper by Allen and Rapraeger (49) describing that HS structural requirements distinct from those for FGF binding are identified for both complex formation and signaling for each FGF and FGF receptor pair, which suggests the usefulness of the HS oligosaccharide library with longer chain sizes which we are going to generate.
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This work was supported in part by Grant-in-aid for Scientific Research on Priority Areas from the Ministry of Education, Culture, Sports, Science and Technology of Japan 14082206, by a preparatory grant for research at the Matrix Glycoconjugate Group, Research Center for Infectious Disease, Aichi Medical University, and by a special research fund from Seikagaku Corp. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.