Journal of Biological Chemistry
Volume 281, Issue 52, 29 December 2006, Pages 40183-40192
Mechanisms of Signal TransductionEpidermal Growth Factor Receptor (EGFR) Antibody Down-regulates Mutant Receptors and Inhibits Tumors Expressing EGFR Mutations*
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This work was supported by NCI, National Institutes of Health Grant R01 CA62212 (to C. L. A.), R01 CA80195 (to C. L. A.), Breast Cancer Specialized Program of Research Excellence (SPORE) Grant P50 CA98131, Lung Cancer SPORE Grant P50 CA90949, and Vanderbilt-Ingram Comprehensive Cancer Center Support Grant P30 CA68485. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. 1S-3S.
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Supported by NCI, National Institutes of Health Grant T32 CA78136.
© 2006 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.