Journal of Biological Chemistry
Volume 282, Issue 8, 23 February 2007, Pages 5641-5652
Protein Synthesis, Post-Translation Modification, and DegradationTrehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein*
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This work was supported in part by the Gates Cambridge Scholarship (to S. S.), Wellcome Trust Senior Fellowship in Clinical Science (to D. C. R.), an MRC programme grant, EU Framework VI (EUROSCA) (to D. C. R.), and BBSRC Grant 8/C17391 (to A. T.). The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. S1-S5.
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Current address: College of Pharmacy, Wuhan University, Wuhan 430072, China.
© 2007 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.