Journal of Biological Chemistry
Protein Structure and FoldingA Novel Family of Sequence-specific Endoribonucleases Associated with the Clustered Regularly Interspaced Short Palindromic Repeats*
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The atomic coordinates and structure factors (code 2i8e) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
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This work was supported, in whole or in part, by National Institutes of Health Grants GM62414 and GM074942 from the Protein Structure Initiative (Midwest Center for Structural Genomics). This work was also supported by Genome Canada (through the Ontario Genomics Institute), the Ontario Research and Development Fund, and the Canadian Foundation for Innovation. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
The on-line version of this article (available at http://www.jbc.org) contains supplemental Table 1, Fig. 1, and additional references.
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Supported by the Intramural Research Program of the National Institutes of Health (National Library of Medicine, National Center for Biotechnology Information).