Transition zone carcinoma of the prostate gland: a common indolent tumour type that occasionally manifests aggressive behaviour
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2020, Urologic Surgical PathologyPrediction of bladder neck invasion and tumor extension to bladder neck margin by prostatic adenocarcinoma: a nomogram using biopsy data including transition zone tumor morphology
2016, Human PathologyCitation Excerpt :Index prostatic adenocarcinoma originating in the transition zone represents approximately 20% of all prostate cancer. Usually these tumors are detected when significantly larger than their peripheral zone (PZ) counterparts, yet have a more favorable prognosis that is attributed to their lower histological grade (2005 Gleason grading system) [1-7]. Biological differences between TZ carcinoma and PZ tumors, remain largely unknown but, transition zone tumors rarely gain access to the seminal vesicles, or posterolateral penetrating peripheral nerves.
A domain constrained deformable (DoCD) model for co-registration of pre- and post-radiated prostate MRI
2014, NeurocomputingCitation Excerpt :The prostate gland consists of internal structures including the peripheral zone (PZ), central zone (CZ), and transition zone (TZ), where the latter 2 structures are jointly referred to as the central gland (CG) [17]. CG tumors have been found to be significantly less aggressive compared to PZ tumors [18] and the different zones can even have different tissue compositions [19], suggesting that they may respond to EBRT differently. Following EBRT, there can be a significant loss in visible zonal anatomy on MRI [20].