Journal of the American Academy of Child & Adolescent Psychiatry
NEW RESEARCHA Replication of the Autism Diagnostic Observation Schedule (ADOS) Revised Algorithms
Section snippets
Participants
Analyses were conducted on data provided by the CPEA, a network of 10 sites funded by the National Institute of Child Health and Human Development and the National Institute of Deafness and Other Communication Disorders, and the STAART program, an NIH-funded network of eight research centers (some of which overlap with CPEA sites) throughout the United States and Canada. This dataset represents 1,259 different participants from 11 different sites, excluding children from Michigan (who were
Comparability of Revision and Replication Samples
The Michigan 2007 sample included more data from children with clinical diagnoses of PDD-NOS than did the CPEA/STAART dataset for all developmental cells (Michigan 2007 N = 439; CPEA/STAART N = 98). In the 2007 sample, the majority of children with nonspectrum diagnoses had been specifically recruited from populations with Down syndrome, fetal alcohol syndrome, and non-ASD language delays to provide a control group against which to assess the predictive validity of the ADOS and ADI-R. In
DISCUSSION
Recently proposed improvements to the algorithm1 resulted in increased comparability across ADOS modules; now each algorithm includes 14 items of similar content. The revised algorithms also better represent observed diagnostic features of ASD in that social, communication, and RRBs contribute to both a measure classification and DSM-IV diagnosis of autism. Predictive value of the ADOS for autism cases generally increased under the revised algorithms in this large independent multisite sample.
REFERENCES (18)
- et al.
Specifying PDD-NOS: a comparison of PDD-NOS, Asperger syndrome, and autism
J Am Acad Child Adolesc Psychiatry.
(2004) - et al.
The use of signal detection theory to assess DSM-III-R criteria for autistic disorder
J Am Acad Child Adolesc Psychiatry.
(1989) - et al.
The Autism Diagnostic Observation Schedule (ADOS): revised algorithms for improved diagnostic validity
J Autism Dev Disord.
(2007) - et al.
The Autism Diagnostic Observation Schedule-Generic: a standard measure of social and communication deficits associated with the spectrum of autism
J Autism Dev Disord.
(2000) - et al.
Cognitive profiles and social-communicative functioning in children with autism spectrum disorders
J Child Psychol Psychiatry.
(2002) - et al.
Interrelationship between Autism Diagnostic Observation Schedule-Generic (ADOS-G), Autism Diagnostic Interview-Revised (ADI-R), and the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) classification in children and adolescents with mental retardation
J Autism Dev Disord.
(2004) - et al.
Autism Diagnostic Observation Schedule Manual
(1999) - et al.
The factor structure of autistic traits
J Child Psychol Psychiatry.
(2004) - et al.
Validity of the autism Diagnostic Interview-Revised
Am J Ment Retard.
(2006)
Cited by (209)
Adaptive behaviors and related factors in children and adolescents with autism spectrum disorder: Report from ELENA cohort
2023, Journal of Psychiatric ResearchDoes the severity of autism symptoms change over time? A review of the evidence, impacts, and gaps in current knowledge
2023, Clinical Psychology ReviewCitation Excerpt :Standardized assessment tools rely heavily on symptom manifestation in childhood and early adolescence. The ADOS, for instance, was originally developed (and has been revised over time) mostly based on symptom presentation in individuals up to 16 years of age (Gotham et al., 2008; Gotham, Risi, Pickles, & Lord, 2007). The ADI-R includes diagnostic cut-off scores for past behaviors only, not accounting for parent-reported current symptom presentation (the Current Behavior Algorithm).
Longitudinal neurodevelopmental profile of a pediatric patient with de novo SPTAN1, epilepsy, and left hippocampal sclerosis
2022, Epilepsy and Behavior ReportsVolumetric Analysis of Amygdala and Hippocampal Subfields for Infants with Autism
2023, Journal of Autism and Developmental Disorders
Article Plus (online-only) materials for this article appear on the Journal's Web site: www.jaacap.com.
This study was supported by NIMHRO1 MH066469 and NIMH R25MH067723.
We gratefully acknowledge the help of Shanping Qiu, Kathryn Larson, and Mary Yonkovit. We thank the families in all CPEA/STAART sites.
This article is the subject of an editorial by Dr. Charles Zeanah in this issue.