Regular Research ArticlesDemographic, Neuropsychological, and Functional Predictors of Rate of Longitudinal Cognitive Decline in Hispanic Older Adults
Section snippets
Participant Sample
Participants in this study were all part of the Sacramento Area Latino Study on Aging (SALSA). The SALSA project is an epidemiologic, longitudinal study of cognitive and functional impairment in older Hispanics. Recruitment methods have been extensively described previously.17., 18., 19. Briefly, SALSA recruitment targeted Census tracts of Sacramento County and neighboring counties with proportional densities of Hispanics >5% based on 1990 and 1998 U.S. Census information. The recruitment
RESULTS
A total of 760 participants were enrolled in the study and had baseline cognitive testing. Of those, 688 individuals completed at least one follow-up evaluation. Forty-one of this 688 had missing data for at least one of the covariates in this study (age, education, gender, acculturation, language of administration), yielding a total sample of 639. Six follow-up evaluations were completed by 217 of the 639, 115 completed five follow-ups, 77 had four follow-ups, 86 had three follow-ups, 72 had
CONCLUSIONS
The aim of this study was to identify the factors that help to determine which individuals are likely to be in the midst of a declining cognitive trajectory. A major finding was that the degree of everyday functional impairment at baseline (as measured by the IQCODE) is a strong predictor of future decline in global cognition, and this was independent of demographic factors. Currently, it is not well understood whether impairments in cognition and daily function develop simultaneously or
References (44)
- et al.
The prevalence of the neuropathological lesions of Alzheimer's disease is independent of race and gender
Neurobiol Aging
(2001) - et al.
Characterization of activities of daily living in individuals with mild cognitive impairment
Am J Geriatr Psychiatry
(2008) - et al.
Mini-mental state: a practical method for grading the cognitive state of patients for the clinician
J Psychiatr Res
(1975) - et al.
Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on Aging
Am J Clin Nutr
(2005) Hispanic population passes 40 million, Census Bureau reports [press release]
(2005)- et al.
Incidence and prevalence of dementia in the Cardiovascular Health Study
J Am Geriatr Soc
(2004) - et al.
Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan
Neurology
(2001) - et al.
Rates of dementia in three ethnoracial groups
Int J Geriatr Psychiatry
(1999) - et al.
Cognitive assessment among minority elderly: possible test bias
J Ment Health Aging
(2001) - et al.
Cognitive test performance among nondemented elderly African Americans and whites
Neurology
(1998)
Variables moderating cultural and ethnic differences in neuropsychological assessment: the case of Hispanic Americans
Clin Neuropsychol
Diagnostic and Statistical Manual of Mental Disorders (Rev. 3rd ed)
MCI is associated with deficits in everyday functioning
Alzheimer Dis Assoc Disord
Characteristic profiles of instrumental activities of daily living in Chinese older persons with mild cognitive impairment
Am J Alzheimers Dis Other Demen
The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): socio-demographic correlates, reliability, validity and some norms
Psychol Med
The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as a screening tool for dementia for a predominantly illiterate Chinese population
Neurology
The measurement of everyday cognition (ECog): Scale development and psychometric properties
Neuropsychology
Application of the Spanish version of the “Informant Questionnaire on Cognitive Decline in the Elderly” in the clinical assessment of dementia
Alzheimer Dis Assoc Disord
A verbal learning and memory test for English- and Spanish-speaking older Mexican-American adults
Clin Neuropsychol
Neuropsychiatric symptoms in Latino elders with dementia or cognitive impairment without dementia and factors that modify their association with caregiver depression
Gerontologist
Prevalence of dementia in older Latinos: the influence of type 2 diabetes mellitus, stroke, and genetic factors
J AM Geriatr Soc
The modified Mini-Mental State (3MS) Examination
J Clin Psychiatry
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The authors thank the participant volunteers and study partners without whom this research would be impossible.
This work was supported by the National Institutes of Health/National Institute of Aging (NIA grants AG 12975, AG 10129, AG 10220, and AG 21511). Presented as a poster at the International Conference on Alzheimer Disease (ICAD) in Chicago, 2008.