The International HapMap Project Web site

  1. Gudmundur A. Thorisson1,2,3,
  2. Albert V. Smith1,2,
  3. Lalitha Krishnan1, and
  4. Lincoln D. Stein1
  1. 1 Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA

Abstract

The HapMap Web site at http://www.hapmap.org is the primary portal to genotype data produced as part of the International Haplotype Map Project. In phase I of the project, >1.1 million SNPs were genotyped in 270 individuals from four worldwide populations. The HapMap Web site provides researchers with a number of tools that allow them to analyze the data as well as download data for local analyses. This paper presents step-by-step guides to using those tools, including guides for retrieving genotype and frequency data, picking tag-SNPs for use in association studies, viewing haplotypes graphically, and examining marker-to-marker LD patterns.

Footnotes

  • [Supplemental material is available online at www.genome.org.]

  • Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.4413105. Freely available online through the Genome Research Immediate Open Access option.

  • 2 These authors contributed equally to the work.

  • 3 Corresponding author. E mail mummi{at}cshl.edu; fax (516) 367-8389.

    • Accepted September 6, 2005.
    • Received July 11, 2005.
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