A second-generation linkage map of the bovine genome.

  1. S M Kappes,
  2. J W Keele,
  3. R T Stone,
  4. R A McGraw,
  5. T S Sonstegard,
  6. T P Smith,
  7. N L Lopez-Corrales, and
  8. C W Beattie
  1. U.S. Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center, Clay Center, Nebraska 68933-0166, USA. kappes@map.marc.usda.gov

Abstract

We report a bovine linkage map constructed with 1236 polymorphic DNA markers and 14 erythrocyte antigens and serum proteins. The 2990-cM map consists of a sex-specific, X chromosome linkage group and 29 sex-averaged, autosomal linkage groups with an average interval size of 2.5 cM. The map contains 627 new markers and 623 previously linked markers, providing a basis for integrating the four published bovine maps. Orientation and chromosomal assignment of all the linkage groups, except BTA20 and BTA22, was provided by 88 markers that were assigned previously to chromosomes. This map provides sufficient marker density for genomic scans of populations segregating quantitative trait loci (QTL) and subsequent implementation of marker-assisted selection (MAS) mating schemes.

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  1. doi: 10.1101/gr.7.3.235 Genome Res. 7: 235-249 Copyright © Cold Spring Harbor Laboratory Press

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