Human Subtelomeric DNA

  1. H. RIETHMAN,
  2. A. AMBROSINI,
  3. C. CASTANEDA,
  4. J.M. FINKLESTEIN,
  5. X.-L. HU,
  6. S. PAUL, and
  7. J. WEI
  1. The Wistar Institute, Philadelphia, Pennsylvania 19104

This extract was created in the absence of an abstract.

Excerpt

Telomeres are dynamic and complex chromosomalstructures. They are essential for genome stability andfaithful chromosome replication, and they mediate keybiological activities including cell cycle regulation, cellular aging and immortalization, movements and localization of chromosomes within the nucleus, and transcriptional regulation of subtelomeric genes (Blasco et al.1999; Feuerbach et al. 2002)...

| Table of Contents