Multiple Sclerosis: Deeper Understanding of Its Pathogenesis Reveals New Targets for Therapy*

Lawrence Steinman; Roland Martin; Claude Bernard; Paul Conlon; Jorge R. Oksenberg

doi:10.1146/annurev.neuro.25.112701.142913

Multiple Sclerosis: Deeper Understanding of Its Pathogenesis Reveals New Targets for Therapy*

Lawrence Steinman, Roland Martin, Claude Bernard, Paul Conlon, and Jorge R. Oksenberg
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Affiliations: ¹Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305; email: [email protected] ²Neuroimmunology Branch, National Institutes of Health, Bethesda, Maryland; email: [email protected] ³Neuroimmunology Laboratory, Department of Biochemistry, La Trobe University, Bundoora, Victoria, 3083 Australia; email: [email protected] ⁴Neurocrine Biosciences, Science Park Drive, San Diego, California; email: [email protected] ⁵Department of Neurology, University of California, San Francisco, California; email: [email protected]
Vol. 25:491-505 (Volume publication date March 2002) https://doi.org/10.1146/annurev.neuro.25.112701.142913
© Annual Reviews

Abstract

▪ Abstract

Recent technological breakthroughs allowing for large-scale analysis of gene transcripts and large-scale monitoring of the immune response with protein chips are revealing new participants in the pathogenesis of multiple sclerosis. Some of these participants may be useful targets for therapy.

Keyword(s): genomics, immunotherapy, microarray, osteopontin, proteomics

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2002-03-01

2024-04-23

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Multiple Sclerosis: Deeper Understanding of Its Pathogenesis Reveals New Targets for Therapy*

Annual Review of Neuroscience 25, 491 (2002); https://doi.org/10.1146/annurev.neuro.25.112701.142913

/content/journals/10.1146/annurev.neuro.25.112701.142913

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Annual Review of Neuroscience

Volume 25, 2002

Review Article

Multiple Sclerosis: Deeper Understanding of Its Pathogenesis Reveals New Targets for Therapy*

Abstract

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