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Safety Assessment of Nanoparticles Cytotoxicity and Genotoxicity of Metal Nanoparticles In Vitro

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There is an urgent need to investigate the mechanisms of action of NMs and to develop testing strategies to assess potential environmental and human hazard. Our study has shown that metal nanoparticles such as iron oxide may induce genotoxic effect. It was inferred that coating and surface properties influence NPs cytotoxicity and genotoxicity.

Keywords: COMET ASSAY; CYTOTOXICITY; DNA DAMAGE; GENOTOXICITY; IRON OXIDE; NANOMATERIAL SAFETY; NANOPARTICLES

Document Type: Research Article

Publication date: 01 January 2011

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  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
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