Journal of Lipid Research
Volume 50, Issue 10, October 2009, Pages 2111-2116
Patient-Oriented and Epidemiological ResearchA nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
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open access
SNP
genetics
replication study
PNPLA3
fatty liver
nonalcoholic steatohepatitis
NASH
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This work was supported in part by grants UBACYT M055 (Universidad de Buenos Aires), PICT 05-25920 and PICT 2006-124 (Agencia Nacional de Promoción Científica y Tecnológica) and Consejo de Investigación de la Ciudad Autonóma de Bs.As. SS, ALB and CJP belong to Consejo Nacional de Investigaciones Científicas (CONICET).
- ADPN
adiponutrin
- ALT
alanine aminotransferase
- AP
alkaline phosphatase
- AST
aspartate aminotransferase
- BMI
body mass index
- df
degree of freedom
- GGT
glutamyl-transferase
- GWAS
genome-wide association studies
- HOMA
Homeostasis Model Assessment
- NAFLD
nonalcoholic fatty liver disease
- NASH
nonalcoholic steatohepatitis
- PNPLA3
patatin-like phospholipase domain containing 3 gene
- SABP
systolic arterial blood pressure
- SNP
single nucleotide polymorphism
- US
ultrasonographic
Abbreviations:
© 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.