Abstract
Background
Elevation of serum cholesterol, or hyperlipidemia, is recognized as one of the major modifiable risk factors in the development of atherosclerosis and cardiovascular disease. On a US population basis, there has been a downward trend in total- and LDL-cholesterol levels, and an increase in cholesterol screening. Nevertheless, previous research suggests that there remain racial/ethnic disparities in the access to and quality of care for hyperlipidemia.
Objective
The aim of this study was to examine the extent of racial/ethnic disparities in the provision of pharmacotherapy, cholesterol screening and diet/nutrition or exercise counseling during US office-based physician-patient encounters (visits) by patients with hyperlipidemia.
Methods
We examined data from the 2005 US National Ambulatory Medical Care Survey for office-based visits for hyperlipidemia for patients aged ≥20 years in terms of prescribing for hyperlipidemia, and the ordering/provision of cholesterol testing, diet/nutrition counseling, and exercise counseling.
Results
Use of pharmacotherapy for hyperlipidemia varied by ethnicity/race (χ2, p<0.05). Physician-ordered/provided cholesterol screening occurred in 44.2% of all office-based visits; 46.5% for Whites, 35.4% for Blacks, and 30.3% for Hispanics (χ2, p< 0.05). Diet/nutrition counseling was ordered/provided in 39.7% of office-based visits; 40.4% for Whites, 32.6% for Blacks, and 39.0% for Hispanics (χ2, p<0.05). Exercise counseling was ordered/provided in 32.1% of office-based visits; 32.7% for Whites, 27.2% for Blacks, and 30.6% for Hispanics (χ2, p<0.05).
Conclusion
These findings reveal a disparity in use of pharmacotherapy for hyperlipidemia, physicianordered/provided cholesterol screening, diet/nutrition counseling, and exercise counseling by ethnicity/race. Further research is required to discern, in greater detail, reasons for the observed differences reported, and to ensure equitable access to established standards of care.
Similar content being viewed by others
References
National Center for Health Statistics. Fastats: cholesterol [online]. Available from URL: www.cdc.gov/nchs/fastats/cholest.htm [Accessed 2008 Jan 18].
American Heart Association. Cholesterol statistics [online]. Available from URL: www.americanheart.org/presenter.jhtml?identifier=536 [Accessed 2008 Jan 18].
Levy D, Brink S. A change of heart: how the people of Framingham, Massachusetts helped unravel the mysteries of cardiovascular disease. New York: Knopf, 2005.
Kathiresan S, Manning AK, Demissie S, et al. A genome-wide association study for blood lipid phenotypes in the Framingham heart study. BMC Med Genet 2007; 8 Suppl. 1: S17.
Weiss LA, Pan L, Abney M, et al. The sex-specific genetic architecture of quantitative traits in humans. Nat Genet 2006; 38(2): 218–22.
Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008; 40(2): 189–97.
Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009; 41(1): 56–65.
Despres JP, Couillard C, Gagnon J, et al. Race, visceral adipose tissue, plasma lipids, and lipoprotein lipase activity in men and women: the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) family study. Arterioscler Thromb Vasc Biol 2000; 20(8): 1932–8.
Carr MC, Brunzell JD, Deeb SS. Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans: role of central obesity and LIPC polymorphisms. J Lipid Res 2004; 45(3): 466–73.
Hu D, Hannah J, Gray RS, et al. Effects of obesity and body fat distribution on lipids and lipoproteins in nondiabetic American Indians: the strong heart study. Obes Res 2000; 8(6): 411–21.
Lee TC, O’Malley PG, Feuerstein I, et al. The prevalence and severity of coronary artery calcification on coronary artery computed tomography in black and white subjects. J Am Coll Cardiol 2003; 41: 39–44.
Detrano R. The ethnic specific nature of mechanisms for coronary heart disease. J Am Coll Cardiol 2003; 41(1): 45–6.
Budoff MJ, Nasir K, Mao S, et al. Ethnic differences of the presence and severity of coronary atherosclerosis. Atherosclerosis 2006; 187(2): 343–50.
Bild DE, Detrano R, Peterson D, et al. Ethnic differences in coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation 2005; 111(10): 1313–20.
Carroll MD, Lacher DA, Sorlie PD, et al. Trends in serum lipids and lipoproteins of adults, 1960–2002. JAMA 2005; 294(14): 1773–81.
US Department of Health and Human Services. Trends in cholesterol screening and awareness of high blood cholesterol: United States, 1991–2003. Morb Mortal Wkly Rep 2005; 54(35); 865–70.
Healthy People 2010. Vol. 1: objectives for improving health [online]. Available from URL: www.healthypeople.gov/Document/HTML/Volume1/12Heart. htm#_Toc490544223 [Accessed 2008 Jan 18].
Cleeman JI, Lenfant C. The national cholesterol education program: progress and prospects. JAMA 1998; 280(24): 2099–104.
Grundy SM, Cleeman JI, Merz CN, et al., on behalf of the Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment III Panel Guidelines. J Am Coll Cardiol 2004; 44(3): 720–32.
Stone NJ, Bilek S, Rosenbaum S. Recent National Cholesterol Education Program Adult Treatment Panel III update: adjustments and options. Am J Cardiol 2005; 96(4A): 53E–9E.
National Heart Lung and Blood Institute. National Cholesterol Education Program: program description [online]. Available from URL: www.nhlbi.nih. gov/about/ncep/ncep_pd.htm [Accessed 2008 Jan 18].
Massey MW, Foley KA, Carter-Edwards L, et al. Disparities in lipid management for African Americans and Caucasians with coronary artery disease: a national cross-sectional study. BMC Cardiovasc Disord 2004; 4: 15.
Carnethon MR, Lynch EB, Dyer AR, et al. Comparison of risk factors for cardiovascular mortality in black and white adults. Arch Intern Med 2006; 166(11): 1196–202.
Thomas AJ, Eberly LE, Davey Smith G, et al. Race/ethnicity, income, major risk factors, and cardiovascular disease mortality. Am J Public Health 2005; 95(8): 1417–23.
Rodriguez C, Pablos-Mendez A, Palmas W, et al. Comparison of modifiable determinants of lipids and lipoprotein levels among African-Americans, Hispanics, and non-Hispanic Caucasians >65 years of age living in New York City. Am J Cardiol 2002; 89(2): 178–83.
Acknowledgments
No funding was used in the preparation of this article. The authors declare no conflicts of interest that are relevant to the content of this article.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Willson, M.N., Neumiller, J.J., Sclar, D.A. et al. Ethnicity/Race, Use of Pharmacotherapy, Scope of Physician-Ordered Cholesterol Screening, and Provision of Diet/Nutrition or Exercise Counseling during US Office-Based Visits by Patients with Hyperlipidemia. Am J Cardiovasc Drugs 10, 105–108 (2010). https://doi.org/10.2165/11532820-000000000-00000
Published:
Issue Date:
DOI: https://doi.org/10.2165/11532820-000000000-00000