Abstract
With the sequencing of the genome of over 150 organisms, the field of biology has been revolutionised. Instead of studying one gene or protein at the time, it is now possible to study the effect of physiological or pathological changes on the expressioin of all genes or proteins in the organism. Proteomics aims at the simultaneous analysis of all proteins expressed by a cell, tissue or organism in a specific physiological condition. Because proteins are the effector molecules in all organsims, it is evident that changes in the physiological condition of an organism will be reflected by changes in protein expression
Keywords: Proteomics, peptidomics, MudPit, ICAT, 2D-DIGE
Combinatorial Chemistry & High Throughput Screening
Title: Gel-Based Versus Gel-Free Proteomics: A Review
Volume: 8 Issue: 8
Author(s): Geert Baggerman, Evy Vierstraete, Arnold De Loof and Liliane Schoofs
Affiliation:
Keywords: Proteomics, peptidomics, MudPit, ICAT, 2D-DIGE
Abstract: With the sequencing of the genome of over 150 organisms, the field of biology has been revolutionised. Instead of studying one gene or protein at the time, it is now possible to study the effect of physiological or pathological changes on the expressioin of all genes or proteins in the organism. Proteomics aims at the simultaneous analysis of all proteins expressed by a cell, tissue or organism in a specific physiological condition. Because proteins are the effector molecules in all organsims, it is evident that changes in the physiological condition of an organism will be reflected by changes in protein expression
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Cite this article as:
Baggerman Geert, Vierstraete Evy, De Loof Arnold and Schoofs Liliane, Gel-Based Versus Gel-Free Proteomics: A Review, Combinatorial Chemistry & High Throughput Screening 2005; 8 (8) . https://dx.doi.org/10.2174/138620705774962490
DOI https://dx.doi.org/10.2174/138620705774962490 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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