Abstract
The photochemistry and use of recently developed photosensitive precursors to nitric oxide (NO) are reviewed. As "caged NO" donors these precursors are able to deliver NO in a spatially and temporally controllable manner. These properties have made such precursors useful in applications in biology and medicine, especially in elucidating neurophysiological roles of NO and in new cancer therapies.
Keywords: photodynamic therapy, diazeniumdiolate, nucleophiles, photolysis, meta substituents, photorelease
Current Topics in Medicinal Chemistry
Title: Photosensitive Precursors to Nitric Oxide
Volume: 5 Issue: 7
Author(s): Christopher M. Pavlos, Hua Xu and John P. Toscano
Affiliation:
Keywords: photodynamic therapy, diazeniumdiolate, nucleophiles, photolysis, meta substituents, photorelease
Abstract: The photochemistry and use of recently developed photosensitive precursors to nitric oxide (NO) are reviewed. As "caged NO" donors these precursors are able to deliver NO in a spatially and temporally controllable manner. These properties have made such precursors useful in applications in biology and medicine, especially in elucidating neurophysiological roles of NO and in new cancer therapies.
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Cite this article as:
Pavlos M. Christopher, Xu Hua and Toscano P. John, Photosensitive Precursors to Nitric Oxide, Current Topics in Medicinal Chemistry 2005; 5 (7) . https://dx.doi.org/10.2174/1568026054679326
DOI https://dx.doi.org/10.2174/1568026054679326 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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