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Licensed Unlicensed Requires Authentication Published by De Gruyter October 9, 2006

Approximate Sample Size Calculations with Microarray Data: An Illustration

  • José A. Ferreira and Aeilko Zwinderman
From the journal Statistical Applications in Genetics and Molecular Biology
https://doi.org/10.2202/1544-6115.1227

We outline a method of sample size calculation in microarray experiments on the basis of pilot data and illustrate its practical application with both simulated and real data. The method was shown to be consistent (as the number of `probed genes' tends to infinity) under general conditions in an earlier, more `theoretical' companion paper. Its implementation requires the values of test statistics, the sample size with which the statistics are computed, and the knowledge of their distribution under the null hypothesis.

Keywords: multiple testing; false discovery rate; sample size calculation; analysis of microarray data
Published Online: 2006-10-9

©2011 Walter de Gruyter GmbH & Co. KG, Berlin/Boston

From the journal
Statistical Applications in Genetics and Molecular Biology
Statistical Applications in Genetics and Molecular Biology
Volume 5 Issue 1
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Reader's Reaction
Reader's Reaction to "Dimension Reduction for Classification with Gene Expression Microarray Data" by Dai et al (2006)
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