Case Report
Cardiac Involvement with Lymphoma: A Review of the Literature

https://doi.org/10.3816/CLM.2008.n.034Get rights and content

Abstract

Current literature suggests that the incidence of cardiac involvement by lymphoma as identified by autopsy varies widely, ranging from 8.7% to 20%. Historically, many cases might have been clinically undetected; however, improved imaging techniques increasingly identify cardiac involvement incidentally. In addition, newer agents resulting in improved cancer therapy outcomes might alter the prevalence and location of metastatic deposits to include more unusual disease sites, including intracardiac locations. We present 2 cases and a review of the literature.

References (38)

  • CD Petersen et al.

    Involvement of the heart and pericardium in the malignant lymphomas

    Am J Med Sci

    (1976)
  • HA McAllister

    Tumours of the cardiovascular system

  • G Barbaro et al.

    Cardiac involvement in the acquired immunodeficiency syndrome: a multicenter clinical-pathological study. Gruppo Italiano per lo Studio Cardiologico dei pazienti affetti da AIDS Investigators

    AIDS Res Hum Retroviruses

    (1998)
  • C Sanfructuoso et al.

    Relapse of multiple myeloma in extramedullary sites after autologous bone marrow transplantation

    Eur J Haematol

    (1996)
  • A Alegre et al.

    Different patterns of relapse after autologous peripheral blood stem cell transplantation in multiple myeloma: clinical results of 280 cases from the Spanish Registry

    Haematologica

    (2002)
  • A Menendez et al.

    Clinical spectrum of extramedullary acute promyelocytic leukemia

    Eur J Haematol

    (2000)
  • JB Aragon-Ching et al.

    CNS metastasis: an old problem in a new guise

    Clin Cancer Res

    (2007)
  • RL Piekarz et al.

    Cardiac studies in patients treated with depsipeptide, FK228, in a phase II trial for T-cell lymphoma

    Clin Cancer Res

    (2006)
  • RA Majano-Lainez

    Cardiac tumors: a current clinical and pathological perspective

    Crit Rev Oncog

    (1997)
  • Cited by (66)

    • Mycosis fungoides: A rare cause of giant cardiac mass

      2022, Journal of Cardiology Cases
      Citation Excerpt :

      Two-dimensional echocardiography remains the first diagnostic approach in the study of a cardiac mass. TEE can help us define more accurately the morphology, implantation, and location of the mass [1]. When used in combination with real-time 3-dimensional echocardiography (RT3DE), TEE offers incremental value for the evaluation of intracardiac masses [3].

    • Primary cardiac lymphoma

      2022, Multimodal Imaging Atlas of Cardiac Masses
    • Non-Hodgkin cardiac lymphomas

      2021, Annales de Cardiologie et d'Angeiologie
    View all citing articles on Scopus

    Electronic forwarding or copying is a violation of US and International Copyright Laws.

    Authorization to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by CIG Media Group, LP, ISSN #1557-9190, provided the appropriate fee is paid directly to Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923 USA 978-750-8400.

    View full text