Original ArticleIncidence of Venous Thromboembolism in Hospitalized Patients vs Community Residents
Section snippets
PATIENTS AND METHODS
Using data resources of the Rochester Epidemiology Project,10 we reviewed a master list of 9046 potential cases to identify the inception cohort of 2218 Olmsted County residents with a first lifetime venous thromboembolism (DVT or PE) during the 25-year period from 1966 through 1990, as described in detail elsewhere.11 We had access to a mean ± SD of 30.5±19.2 years (median, 30 years) of documented medical history before the first diagnosis of venous thromboembolism in these patients. Diagnosis
RESULTS
From 1980 through 1990, the time frame covered in the current analysis, 911 Olmsted County residents experienced their first lifetime event of definite, probable, or possible venous thromboembolism. Of these residents, 253 (28%) had been hospitalized for some reason other than a diagnosis of DVT or PE. This number represents fewer than half of the 658 cases observed among Olmsted County residents who were not hospitalized at onset of thromboembolism. However, the population of hospitalized
DISCUSSION
Our study demonstrates that the overall age- and sex-adjusted incidence of venous thromboembolism is more than 100-fold higher among hospitalized patients compared with community residents; if cases occurring in recently hospitalized community residents and community nursing home residents are excluded, the in-hospital incidence is more than 260-fold higher compared with the incidence among community residents. Based on National Hospital Discharge Survey hospitalization rates, we estimate that
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This study was supported in part by grants HL46974 and AR30582 from the National Institutes of Health.
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Dr Silverstein is now at the Center for Health Care Research, Medical University of South Carolina, Charleston.