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CC BY-NC-ND 4.0 · Asian J Neurosurg 2012; 7(02): 61-65
DOI: 10.4103/1793-5482.98645
ORIGINAL ARTICLE

The study of systemic general circulation disturbance during the initiation of therapeutic hypothermia: Pit fall of hypothermia

Mitsuru Honda
Department of Critical Care Center, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Kyosuke Yokota
Department of Critical Care Center, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Ryo Ichibayashi
Department of Critical Care Center, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Katsunori Yoshihara
Department of Critical Care Center, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Hiroyuki Masuda
1   Department of Neurosurgery, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Hiroyuki Uekusa
1   Department of Neurosurgery, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Yoshikatsu Seiki
1   Department of Neurosurgery, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Jun Nomoto
1   Department of Neurosurgery, Toho University Medical Center, Omori Hospital, Ota-ku, Tokyo
,
Takeki Nagao
2   Department of Neurosurgery, Toho University Medical Center, Sakura Hospital, Ota-ku, Tokyo
,
Taichi Kishi
3   Education Planning and Development, School of Medicine, Toho University, R and D Division, Anzai Medical Co., Ltd, Ota-ku, Tokyo
,
Shigeru Sase
4   Faculty of Medicine, Toho University, R and D Division, Anzai Medical Co., Ltd, Ota-ku, Tokyo
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Aims: Neurointensive care has reduced the mortality and improved the outcome of patients for severe brain damage, over recent decades, and made it possible to perform this therapy in safety. However, we have to understand the complications of this therapy well. The purpose of our study was to determine the systemic circulation disturbance during the initiation of therapeutic hypothermia by using this continuous neurointensive monitoring system. Materials and Methods: Ten severe brain damage patients treated with hypothermia were enrolled. All patients had Glasgow Coma Scale (GCS) less than or equal to 8, on admission. Results: We verified that heart rate, cardiac output, and oxygen delivery index (DO2I) decreased with decreasing core temperature. We recognized that depressed cardiac index (CI) was attributed to bradycardia, dehydration, and increased systemic vascular resistance index (SVRI) upon initiation of hypothermia. Conclusion: Although the hypothermia has a therapeutic role in severe brain damage patients, we have to carry out this therapy while maintaining their cardiac output using multimodality monitoring devices during hypothermia period.

Key-words:

Hypothermia - severe brain damage - systemic general circulation disturbance


Publication History

Article published online:
27 September 2022

© 2012. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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